問題的答案無所不包論文書籍站
臺北醫學大學 保健營養學研究所 趙振瑞所指導 Sintha Dewi Purnamasari的 台灣高血脂青壯年婦女富含植物性或動物性之飲食型態與貧血的關聯性：2001年至2015年全國人口之研究 （2019），提出SQ lab 611關鍵因素是什麼，來自於Hyperlipidemia、anemia、plant-rich diet、animal-rich diet。
而第二篇論文國防醫學院 藥理學研究所 施志勤所指導 陳頡翰的 熱中暑引發大鼠血小板活性低下之調控機制 （2017），提出因為有 熱中暑、血小板、凝血障礙的重點而找出了 SQ lab 611的解答。
台灣高血脂青壯年婦女富含植物性或動物性之飲食型態與貧血的關聯性：2001年至2015年全國人口之研究
為了解決SQ lab 611 的問題，作者Sintha Dewi Purnamasari 這樣論述：
AbstractBackground: Recent evidences suggest that the popularity of plant-based food among teenagers and young people, especially women, is increasing. There is still a debate whether vegetarians, in particular plant-based diets, are able to derive the quantities of essential nutrients, like vitami
ns D, iron, calcium and n-3 long-chain fatty acids. In addition, heme iron can be more easily absorbed in terms of bioavailability than nonheme iron.Methods: This study involved 22,631 women participants between 2001 and 2015 aged between 20 and 45 years from the MJ Health Screening Institute Databa
se. In this study, the demographic, lifestyle, medical history, and dietary assessment using semi quantitative-food frequency questionnaire (SQ-FFQ) were included. In addition, measurement of anthropometric (body weight, height, body fat, and hip circumference) and biochemical data (complete blood c
ount, blood lipids test, and CRP) also were retrieved. Statistical analysis (e.g. multivariable linear regression, logistic regression) was performed to clarify the relationship between plant or animal-rich dietary pattern and anemia related biomarkers in hyperlipidemia subjects.Results: This result
indicated that the plant-rich diet (PR diet) + animal-low diet (AL diet) group had a significantly lower prevalence of overweight (19%), obesity (15.9%), central obesity (16.1%), current smoking (10.6%), total cholesterol (15.8%), LDL-C (15.5%) and it also had a lower mean of C-reactive protein (20
.6 ± 31.4), hemoglobin (12.9 ± 1.4), and hematocrit (38.8 ± 3.6). In contrast, in the PL diet + AL diet group, participants tended to have a higher prevalence of underweight (30.0%) and current smoker (34.3%). In logistic regression analysis, after full adjusting for age, lifestyle (current smoker,
physical activity, sleep duration, current vegetarian), anthropometry status (BMI and WC) (Model 3), both dietary habits of PR diet + AL diet and PL diet + AR diet have been stayed to be significantly associated with moderately to severely anemia (PR diet + AL diet OR 1.22, 95% CI: 1.04 to 1.43, P =
0.0151; PL diet + AR diet OR 0.76, 95% CI: 0.64 to 0.92, P = 0.0040)Conclusions: The present study indicates the variability of dietary habits and anemia among hyperlipidemic patients which are important considerations in this study to consume balance diet. High plant-based was positively associate
d with a lower blood lipid biomarker. However, Subjects with high animal-based diet group generally had greater hemoglobin, hematocrit and red blood cell concentrations and it was 13% to be protective from anemia.Keywords: Hyperlipidemia, anemia, plant-rich diet, animal-rich diet
熱中暑引發大鼠血小板活性低下之調控機制
為了解決SQ lab 611 的問題，作者陳頡翰 這樣論述：
熱中暑（Heatstroke）是一種因熱壓力致使體溫失控而引發多重器官功能異常的致命性疾病。熱中暑患者常見出血傾向（hemorrhagic diathesis）與凝血障礙（coagulopathy）等嚴重併發症。流行病學研究顯示，嚴重的凝血障礙容易導致出血而發展為低血壓性休克，並與熱中暑患者的死亡率高度相關。目前認為，熱中暑引發的發炎反應會過度活化凝血因子造成全身性的血栓形成，同時消耗大量的凝血因子與血小板，這些機制的共同作用是造成熱中暑患者凝血障礙的主因。然而，血小板在熱中暑引發的凝血障礙中所扮演的角色仍不清楚。因此，我們評估熱中暑大鼠血小板的功能變化，並探討造成其活性改變的機制。本實驗將
成年的雄性Wistar大鼠麻醉後置入已預熱至42℃ 之烘箱（控制組則控制烘箱溫度為25℃）中，待其核心體溫達44℃ 時迅速移出，接著在出烘箱後的六小時內持續記錄其平均動脈壓、心跳速率、對正腎上腺素的昇壓反應、血小板數量以及血清生化數值的變化。於動物犧牲時，取出全血製備血小板豐富血漿（platelet-rich plasma, PRP）、血小板缺乏血漿（platelet-poor plasma, PPP）以及洗滌血小板（washed platelets, WP）；另取出部分PRP以自體來源的PPP校正血小板濃度為 300×〖10〗^3/μL，得到標準化PRP（normalized PRP, nP
RP）。接著以光學密度法測定PRP、WP和nPRP對adenosine diphosphate（ADP）、protease-activated receptor-4 agonist peptide（PAR4-amide）、collagen和arachidonic acid（AA）等活化劑所產生之凝集反應。實驗結果顯示，熱中暑動物的PRP與nPRP對各活化劑的活性顯著低於控制組，而WP的活性兩組間則沒有差異，顯示熱中暑動物的血小板活性會被血漿中的物質所抑制。分別加入不同藥理作用的抑制劑後，ODQ能改善熱中暑組PRP對ADP與collagen的活性；istradefylline則能改善熱中暑組PR
P對ADP、PAR4-amide與collagen的活性；而SQ-22,536能改善熱中暑組PRP對collagen的活性。此外，加入apyrase後，能顯著提升PRP對所有活化劑的活性，然而，在PRP的酸鹼值上兩組間無統計差異。綜合上述的結果，熱中暑會造成血小板的活性顯著下降，其機制與血液酸化無關，可能是透過血漿中的因子過度活化血小板內soluble guanylate cyclase路徑與adenosine/adenylate cyclase路徑，以及造成血小板purinergic receptors的去敏感化。因此，熱中暑造成的血小板活性低下可能與患者的凝血障礙有關，在熱中暑的治療上值得
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