問題的答案無所不包論文書籍站
國立屏東大學 應用化學系碩士班 廖美儀所指導 鄭卉真的 金銀銅三合金奈米空球用於降解環境有毒化合物 （2021），提出Benz replacement關鍵因素是什麼，來自於金銀銅奈米材料、表面增強拉曼散射、降解有毒化合物。
而第二篇論文高雄醫學大學 醫藥暨應用化學系博士班 王麗芳所指導 Siva sankari Sivasoorian的 功能性胜肽偶聯金奈米棒在靶向光熱治療之應用 （2021），提出因為有 的重點而找出了 Benz replacement的解答。
Benz replacement進入發燒排行的影片
復古March DIY更換煞車燈炮【煞車燈不會亮】白同學國產車DIY
https://www.youtube.com/watch?v=4_cba-THsZk
煞車燈異常只花６元修好它【MARCH 煞車燈開關拆裝 DIY】
https://www.youtube.com/watch?v=7Mb3m4lAi0k
DIY煞車開關分解維修【BMW E36 煞車燈不亮】
https://www.youtube.com/watch?v=0UkQO39SOQU
BENZ煞車開關更換DIY【 賓士BENZ W210通病．BAS . ASR亮燈】BENZ DIY
https://www.youtube.com/watch?v=yxf_FMHEfEo
金銀銅三合金奈米空球用於降解環境有毒化合物
為了解決Benz replacement 的問題，作者鄭卉真 這樣論述：
本研究開發具有光學特性的金銀銅三合金複合型奈米材料，我們以Cu@Cu2O@PSMA奈米顆粒為起始模板，透過調整初始金和銀離子前驅物濃度可以控制金和銀的比例，透過電化學置換反應形成金銀銅合金奈米顆粒，隨著四氯金酸/硝酸銀添加比例增加，粒徑從 30 nm 到 70 nm呈現出濃度依賴性的尺寸增長，奈米顆粒的形狀從中空奈米結構變成實心奈米結構。金銀銅三合金奈米顆粒，具有紅外光吸收的光學特性，利用其表面增強拉曼散射偵測孔雀石綠及亞甲基藍，抑或是化學吸附的4-硝基苯硫酚(4-NTP)皆有不錯的表現，相較於金銅奈米粒子其SERS增強了28-30倍，而在降解4-NA為p-PDA以及降解4-NP為4-AP的
催化反應中也具有不錯的催化活性，其k值分別為3.36 × 10-3 s-1以及5.08 × 10-3 s-1，其催化活性較金銅奈米粒子優於2-3倍，在環境中已充斥各種污染物與毒化物的現況下，我們的奈米粒子已準備好應用於 SERS檢測汙染物以及降解環境有毒化合物。
功能性胜肽偶聯金奈米棒在靶向光熱治療之應用
為了解決Benz replacement 的問題，作者Siva sankari Sivasoorian 這樣論述：
Antibiotic resistance and impaired wound healing are the main challenges associated with wound care caused by multidrug-resistant (MDR) pathogens. To combat the bacterial wound infection and accelerate wound closure, we synthesized an antimicrobial peptide-conjugated (LL-37) gold nanorod and a neur
opeptide-conjugated gold nanorod that can bind with bacteria based on electrostatic interaction. The GNR-peptide conjugates showed good biocompatibility, sufficient stability, enhanced targeting, the potential photothermal killing of bacteria, and possible acceleration of wound healing. The photo-bi
omodulation properties of NIR improved the wound closure rates through enhanced cell migration.The multifunctional LL37-conjugated GNRs significantly enhanced photothermal therapeutic outcomes based on bacterial targeting with promising wound healing properties (Chapter 1). We studied the neuropepti
de (ANGIOPEP-2) conjugated gold nanorod’s efficiency to enhance the cellular uptake of the metal nanoparticle in order to achieve effective photothermal therapy in gliomas. We evaluated five glioma cells for LRP1 expression as ANGI-2 targets specificity for this peptide. Among the five glioma cells
(C6, F98, AST1,9L, and U87), C6 has the highest LRP1 expression, hence chosen as the cell model for further studies. We evaluated the cell viability with NIH3T3 fibroblast cells, and the conjugate showed no significant cytotoxicity. The in vitro therapeutic effect of the conjugate with sham or laser
exposure showed 40% cell death assessed by MTT assay. We evaluated the ROS production with two time periods of exposure, 12 min and 24 min. The conjugate with laser exposure showed higher ROS production at 24 min, provided that time increment of laser exposure will help improve the oxidative stress
. To evaluate the cell death pattern, we used caspase and RIPK 1 inhibitors to study their effect on the PTT induced by the conjuga. The cell death pattern was found to be caspase-dependent apoptosis. We further evaluated the expression of tumor suppressor p53, apoptosis effectors caspase-3/7, and B
cl-2 protein using western blotting. Western blotting studies indicated the conjugate follows two different pathways depending on the sham or laser exposure. With sham exposure, theconjugate follows p53/Bcl-2 mediated autophagy inhibition, causing low or no cytotoxicity to glioma cells. With laser e
xposure followed by increased oxidative stress, the conjugate followed the p53/miR34a/Bcl-2 mediated caspase pathway of apoptosis and enhanced cell death.