Atlas的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列各種有用的問答集和懶人包

An Atlas of Small Animal Ocular Surgery

為了解決Atlas的問題，作者 這樣論述：

Rick became a Diplomate of the European College of Veterinary Ophthalmologists (DipECVO) in 2007. He is a Spanish national and followed his education in the US and the UK. He obtained a Bachelor’s degree in Biology in St. Thomas Aquinas College, in New York in 1994 and a DVM after attending Ross and

Louisiana State Universities in 1999. He commenced his specialty training in the US and later moved to the EU where he attended the Universidad Autónoma de Barcelona (UAB) to obtain his European veterinary qualification in 2002. Since, Rick obtained his RCVS certificate in ophthalmology (UK) and co

mpleted his residency training at the University of Glasgow and the Eye Veterinary Clinic, in Herefordshire, England, after which he obtained his DipECVO in 2007. Then, he headed the ophthalmology service in a private practice in England from 2006 until 2011. That same year he joined the Royal Veter

inary College of the University of London as a Lecturer to re-launch and lead the new Ophthalmology Service at the Queen Mother Hospital for Animals (QMHA).David graduated from the University of Edinburgh in 1992 and, after a period in general practice, completed a PhD at the University of Cambridge

in the molecular genetics of inherited eye diseases of dogs. Following this he moved to the University of Bristol for a three year clinical residency in veterinary ophthalmology. After this he was appointed Lecturer in Veterinary Ophthalmology at Bristol University Veterinary School, a post that he

held for three years before joining Davies Veterinary Specialists in October 2003 to jointly run their ophthalmology service. He holds both RCVS and European Diplomas in Veterinary Ophthalmology and is an RCVS recognised Specialist in Veterinary Ophthalmology and European Veterinary Specialist in O

phthalmology.

Atlas進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Atlas的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Atlas of Gynecologic Pathology: A Pattern Based Approach

為了解決Atlas的問題，作者Murdock, Tricia,Savage, Johanna 這樣論述：

低腔壓高濃度過氧化氫混合式火箭引擎之研究

為了解決Atlas的問題，作者林育宏 這樣論述：

本論文為混合式火箭系統入軌段火箭引擎的前期研究，除了高引擎效率的要求外，更需要精準的推力控制與降低入軌段火箭的結構重量比，以增加入軌精度與酬載能力。混合式火箭引擎具相對安全、綠色環保、可推力控制、管路簡單、低成本等優點，並且可以輕易地達到引擎深度節流推力控制，對於僅能單次使用、需要精準進入軌道的入軌段火箭推進系統有相當大的應用潛力。其最大的優點是燃料在常溫下為固態、易保存且安全，即使燃燒室或儲存槽受損，固態的燃料也不會因此產生劇烈的燃燒而導致爆炸。雖然混合式推進系統有不少優於固態及液態推進系統的特性，相較事先預混燃料與氧化劑的固態推進系統及可精準控制氧燃比而達到高度燃燒效率的液態推進系統，混

合式推進系統有擴散焰邊界層燃燒特性，此因素導致混合式推進系統的燃料燃燒速率普遍偏低，使得設計大推力引擎設計時需要長度較長的燃燒室來提供足夠的燃料燃燒表面積，也導致得更高長徑比的火箭設計。針對此問題，本論文利用渦漩注入氧化劑的方式，增加了氧化劑在引擎內部的滯留時間，並藉由渦旋流場提升氧化劑與燃料的混合效率以及燃料耗蝕率；同時降低引擎燃燒室工作壓力以研究其推進效能，並與較高工作壓力進行比較。本論文使用氮氣加壓供流系統驅動90%高濃度過氧化氫 (high-test peroxide) 進入觸媒床，並使用三氧化二鋁 (Al2O3) 為載體的三氧化二錳 (Mn2O3) 觸媒進行催化分解，隨後以渦漩注入的

方式注入燃燒腔，並與燃料聚丙烯（polypropylene, PP）進行燃燒，最後經由石墨鐘形噴嘴 (bell-shaped nozzle) 噴出燃燒腔後產生推力。實驗部分首先透過深度節流測試先針對原版腔壓40 barA引擎在低腔壓下的氧燃比 (O/F ratio)、特徵速度 (C*)、比衝值 (Isp) 等引擎性能進行研究，提供後續設計20 barA低腔壓引擎的依據，並整理出觸媒床等壓損以及燃燒室等流速的引擎設計轉換模型；同時使用CFD模擬驗證渦漩注射器於氧化劑全流量下 (425 g/s) 的壓損與等壓損轉換模型預測的數值接近 (~1.3 bar)。由腔壓20 barA 引擎的8秒hot-f

ire實驗結果顯示，由於推力係數 (CF) 在低腔壓引擎的理論值 (~1.4) 相較於腔壓40 barA引擎的推力係數理論值 (~1.5) 較低，因此腔壓20 barA引擎的海平面Isp相較於腔壓40 barA引擎的Isp 低了約13 s，但是兩組引擎具有相近的Isp效率 (~94%)，且長時間的24秒hot-fire測試顯示Isp效率會因長時間燃燒而提升至97%。此外，氧化劑流量皆線性正比於推力與腔壓，判定係數 (R2) 也高於99%，實現混合式火箭引擎推力控制的優異性能。透過燃料耗蝕率與氧通量之關係式可知，低腔壓引擎在相同氧化劑通量下 (100 kg/m2s) 較腔壓40 barA引擎降低

了約15%的燃料耗蝕率，因此引擎的燃料耗蝕率會受到腔體壓力轉換的影響而變動，本論文也針對此現象歸納出一校正方法以預測不同腔壓下的燃料耗蝕率，此校正後的關係式可提供未來不同腔壓引擎燃料長度設計上的準則。最後將雙氧水貯存瓶的上游氮氣加壓壓力從約58 barA降低至38 barA並進行8秒hot-fire測試，結果顯示仍能得到與過往測試相當接近的Isp效率 (~94%)，而此特性除了能讓雙氧水及氮氣貯存瓶擁有輕量化設計的可能性，搭配具流量控制的控制閥也有利於未來箭體朝向blowdown type型式的設計，因此雙氧水加壓桶槽上的氮氣調壓閥 (N2 pressure regulator valve)

將可省去，得以降低供流系統的重量，並增加箭體的酬載能力，對於未來箭體輕量化將是一大優勢。