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Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact

為了解決100mph to km/h的問題，作者 這樣論述：

Stefania Boccia, PhD, DSc, MS, is Full professor of Hygiene, Preventive Medicine and Public Health at Università Cattolica del Sacro Cuore (UCSC) in Rome, Italy. She is the Director of the Section of Hygiene of the Department of Health Science and Public Health of UCSC and President of the Public He

alth Epidemiology Section of European Public Health Association (EUPHA). A Biologist by training and Specialist in Clinical Pathology, she obtained a Master of Science in Epidemiology and Biostatistics and a Doctor of Science and PhD in Genetic Epidemiology at the Erasmus MC in Rotterdam, the Nether

lands. From 2016 to 2018 she was Adjunct Professor at Mount Sinai Medical School in New York, NY, USA. In 2018 she founded the spin-off ＂Vihtali srl＂ (Value In Health Technology and Academy for Leadership & Innovation) at UCSC. She currently coordinates the project titled ＂European network staff eXc

hange for integrAting precision health in the health Care sysTems＂ (ExACT) funded by the European Commission (EC) within the H2020 Marie-Slodowska Curie projects (MSCA-RISE). She is currently partner of several EU-funded projects; among them is ＂Integrating China in the International Consortium for

Personalised Medicine＂ (IC2PerMed, CSA) as a member of the Coordinating group. She is author and co-author of 216 scientific publications; her h-index (Scopus) is 37 and citation count is 5350.Róza Ádány, MD, PhD, DSc, is a medical doctor with specialization in the field of preventive medicine and p

ublic health. She is Professor of public health at the University of Debrecen, Hungary; founding Dean of the Faculty of Public Health; leader of the Public Health Research Group funded by the Hungarian Academy of Sciences; head of the WHO Collaborating Centre on Vulnerability and Health; and Preside

nt of the Public Health Genomics Section of the European Public Health Association. She also acts as president of the Hungarian Association of Public Health Training and Research Institutes, chief editor of the journal ’Népegészségügy’ (Public Health), editorial member of the European Journal of Pub

lic Health, associate editor of the Frontiers in Public Health journal, and Vice-Chair of the European Advisory Committee on Health Research for WHO European Region. She was chairperson of the Association of Schools of Public Health in the European Region (ASPHER) between 2001-2003. She contributed

as expert adviser to the development of the revised version of the Health for All and the draft of the Health 2020 strategies of the WHO Europe. She is author and co-author of 237 scientific publications; her h-index (Scopus) is 33 and citation count (Scopus) is 4634. She received several prestigiou

s Hungarian and international awards in acknowledgement of her work.Paolo Villari, MD, MPH, is Full professor of Hygiene and, since 2015, is Director of the Department of Public Health and Infectious Diseases at Sapienza University of Rome, Italy, where he also is Member of the Academic Senate. A gr

aduate in Medicine and Surgery and Specialist in Hygiene and Preventive Medicine, he obtained the Master’s Degree in Public Health at Harvard University. As former President of the Epidemiology Section of the European Public Health Association (EUPHA) in the years 2004-2006 and national delegate for

Italy to the Federation of European Academies of Medicine (FEAM) from 2007 to 2013, he was Deputy Secretary General of the FEAM from 2010 to 2013. A member of the Scientific Committee at the Ministry of Health, Directorate General of Health Planning, from 2011 to 2013, he is currently Chairman of t

he National Committee for the Verification of measles and rubella elimination. He is responsible for international and national research projects, funded by the University, Ministry of Health, Ministry of University, EU in the fields of epidemiology of infectious diseases, health management and heal

th services research. He is author and co-author of 165 publications (Scopus); his h-index (Scopus) is 32 and citation count (Scopus) is 3096.Martina C. Cornel, MD, PhD, is professor of community genetics and public health genomics at the Amsterdam University Medical Centers, location VUMC, in the D

epartment of Clinical Genetics, Section of Community Genetics, and the Amsterdam Public Health Research Institute, in The Netherlands. She is a physician and epidemiologist. After 2000 she mainly worked on the responsible implementation of genetic testing and screening. She is vice chair of the Neth

erlands patients’ umbrella organization for rare and genetic diseases (VSOP: https: //vsop.nl/). She is co-chair of the Public and Professional Policy Committee of the European Society of Human Genetics. She is a member of the Netherlands Health Council and two of its standing Committees (Population

Screening and Advisory Council). She is chair of the Netherlands Program Committee Neonatal Heelprick Screening. She is Editor-in-Chief of the Journal of Community Genetics. She is author and co-author of 288 publications (Scopus); her h-index (Scopus) is 37 and citation count (Web of Science Core

collection) is 3891.Corrado De Vito, MD, PhD, is an epidemiologist and Associate professor of Hygiene at the Department of Public Health and Infectious Diseases at Sapienza University of Rome, Italy. Since 2020 he is the Director of the Residency of Hygiene and Preventive Medicine of Sapienza Univer

sity of Rome. Corrado De Vito graduated in Medicine and Surgery, and obtained a PhD in Infectious Diseases, Microbiology and Public Health at Sapienza University of Rome. He is principal investigator or partner of several national and international projects in the fields of vaccines and vaccination,

chronic care models and public health genomics. In the latter field he is partner of the ＂European network staff eXchange for integrAting precision health in the health Care sysTems＂ (ExACT) funded by the European Commission (EC) within the H2020 Marie-Slodowska Curie projects (MSCA-RISE). He is au

thor and co-author of 100 publications (Scopus); his h-index (Scopus) is 20 and citation count (Scopus) is 1375.Roberta Pastorino, PhD, is a post-doc fellow at the Department of Woman and Child Health and Public Health--Public Health Area at Fondazione Policlinico Universitario A. Gemelli IRCCS in R

ome, Italy. She is a Bioengineer with a PhD in Biostatistics and a Master in Genetic Epidemiology. She is Vice-President of the Public Health Genomics Section of the European Public Health Association (EUPHA) and currently Project Manager of the project titled ＂European network staff eXchange for in

tegrAting precision health in the health Care sysTems＂ (ExACT) funded by the European Commission (EC) within the H2020 Marie-Slodowska Curie projects (MSCA-RISE). She is author and co-author of 66 scientific publications; her h-index (Scopus) is 16 and citation count is 614.

Bioethical Decision Making in Nursing

為了解決100mph to km/h的問題，作者Husted, Gladys L., Ph.D., R.N./ Husted, James H./ Scotto, Carrie 這樣論述：

FOURTH EDITION NAMED A 2013 DOODY'S CORE TITLE "This book provides a systematic approach to bioethical decision making, a process that can help clarify situations where right and wrong are not clearly defined. This is] a valuable book for ethics and theory courses." Score: 100, 5 stars--Doody'sMor

e relevant today than ever, Husted's classic nursing ethics text provides a practical framework to help nurses engage with patients to make difficult ethical decisions. It delivers a systematic approach to bioethical decision making that can help clarify situations where "right" and "wrong" are not

clearly defined. An abundance of case studies provides practice in bioethical decision making, with nearly 45 bioethical dilemmas analyzed in detail. The fifth edition has been reorganized and rewritten to facilitate increased readability and to engage readers more fully in learning. It includes two

new chapters, Moral Distress and Nursing Practice Intersections: Legal Decision Making Within a Symphonological Ethical Perspective, additional case studies, and abundant tables, diagrams, and graphics that reinforce the text discussion. Instructor resources are also available for adopters of the t

ext.The book is grounded in the concept of "symphonia," which, within the health care arena, is the study of agreements between health care professionals and patients and the ethical implications of these agreements. It is intended to promote the welfare of both patient and health care provider. The

new chapter on moral distress discusses futile care among other causes of moral distress and offers coping techniques for situations in which a nurse has an ethical issue with a standard of care but is powerless to change that care. The other new chapter, Nursing Practice Intersections: Legal Decis

ion Making Within a Symphonological Ethical Perspective, focuses on situations that can be interpreted as either moral and illegal, or immoral and legal. The fifth edition also features a new section on ethical colleagueship, providing support to relieve common dilemmas among health care professiona

ls.NEW TO THE FIFTH EDITION: Reorganized and rewritten for ease of comprehension and increased reader engagementIncludes two new chapters, Moral Distress and Nursing Practice Intersections: Legal Decision Making Within a Symphonological Ethical PerspectiveProvides more tables, diagrams, and graphics

to clarify text discussionProvides objectives at the beginning of each chapterExpanded study guide at the end of each chapterDelivers new case studies that are analyzed in depthIncludes four humorous scenarios in which the humor easily reveals the obvious from the obscureAddresses ethical colleague

shipGLADYS L. HUSTED, PhD, MSNEd, RN, is professor emeritus of nursing at Duquesne University, Pittsburgh, Pennsylvania. She received a master's in nursing education from the University of Pittsburgh, where she also completed her PhD in curriculum and supervision. She was awarded the title of Schoo

l of Nursing Distinguished Professor in 1998. She has retired from full-time employment at Duquesne University but continues to teach part time in the MSN and PhD programs. Her main area of expertise is in bioethics. She continues to write and consult. Her other areas of expertise are in curriculum

design, instructional strategies, and theory development. Dr. Husted's website can be accessed at www.duq.edu/nursing/faculty/hustedJAMES H. HUSTED is an independent scholar. He is a member of the American Philosophical Association and the North American Spinoza Society. He has been a member of the

high IQ societies, Mensa and Intertel. He was the philosophy expert for Dial-An-M for Mensa, as well as the philosophy editor of Integra, the journal of Intertel.CARRIE J. SCOTTO, PhD, RN, is an associate professor at the University of Akron School of Nursing, where she teaches pathophysiology and

pharmacology. She earned her BSN and MSN from the University of Akron and her PhD from Duquesne University. As an educator and clinician, she has a vested interest in bioethics. She has served more than 20 years at the bedside as a critical care nurse. Her research related to adherence to prescribed

treatment for cardiac patients and therapeutic clinical interventions for critically ill patients has been presented nationally and is published in professional journals. She is a member of Sigma Theta Tau International, American Association of Critical-Care Nurses, American Association of Cardiova

scular and Pulmonary Rehabilitation, and Preventive Cardiovascular Nurses Association.KIMBERLY M. WOLF, PhD, PMHCNS-BC, is a psychiatric-mental health clinical nurse specialist at Hennepin County Medical Center, Minneapolis, Minnesota, and the psychiatric-mental health nurse practitioner track dire

ctor at the University of North Dakota, Grand Forks, North Dakota. She also teaches part time as an adjunct faculty in the nursing department at Duquesne University, Pittsburgh, Pennsylvania. She received a master's degree in science in advanced practice psychiatric-mental health nursing from the Un

iversity of North Dakota. She received a PhD from Duquesne University in 2013. She enjoys her work as a full-time provider in the busy urban county hospital but also values actively teaching in master's and doctoral programs. Her interest areas are bioethics, cultural competency, and psychiatric-men

tal health advanced practice nursing.ContributorSUZANNE EDGETT COLLINS, JD, PhD, MPH, RN, is a nurse-attorney with experience in the areas of medical and nursing malpractice, legal and bioethics education of allied health care practitioners, and consultation practice in licensure defense, health la

w/policy, and health care risk management

運用奈米鉑-金雙金屬顆粒增強近紅外光吸收於癌症光熱治療法

為了解決100mph to km/h的問題，作者吳鈞裕 這樣論述：

摘要 iiAbstract iii圖目錄 vii表目錄 ix誌謝 x第一章 前言 11.1研究背景與目的 11.2實驗流程圖 2第二章 文獻回顧與理論 32.1奈米材料 32.1.1奈米鉑 32.1.2奈米金 32.2光熱治療 42.3卵巢癌 42.3.1卵巢癌診斷 52.3.2卵巢癌的治療 62.4乳腺癌 62.4.1乳腺癌的診斷 72.4.2乳腺癌的治療 8第三章 實驗材料與分析方法 103.1實驗材料與藥品 103.2實驗儀器 113.3材料製備 1

23.4材料分析 123.4.1穿透式電子顯微鏡及能量色散-X-射散光譜(Energy Dispersive Spectroscopy)分析 123.4.2材料粒徑大小統計 123.5感應耦合電漿光學發射光譜儀分析(ICP-OES Assay) 133.6細胞實驗 133.6.1培養基製備 133.6.2細胞解凍 153.6.3細胞培養 153.6.4細胞計數 153.6.5細胞保存 163.7細胞存活率分析(MTT Assay) 163.7.1 含有分散劑之Pt/Au NPs及Au NPs毒性分析 173.7.2未含有分

散劑之Pt/Au NPs及Au NPs毒性分析 173.8光熱治療 183.8.1 Pt/Au NPs及Au NPs光熱治療 183.8.2 Pt/Au NPs及Au NPs對細胞之光熱治療 183.9動物實驗 193.9.1腫瘤動物模式誘發與建立 193.9.2光熱治療動物 203.9.3動物犧牲組織與採樣 203.9.4動物組織切片與病理分析 203.10實驗統計分析 20第四章 結果與討倫 214.1 TEM表面形貌觀察與粒徑分析 214.1.1 Pt/Au NPs及Au NPs離心前後之形貌 214.1.2

Pt/Au NPs及Au NPs不同濃度之形貌 214.2感應耦合電漿光學發射光譜儀分析(ICP-OES Assay) 224.3細胞存活率分析(MTT Assay) 224.3.1 Pt/Au NPs及Au NPs含有分散劑對SKOV-3之MTT試驗及T-test分析 234.3.2 Pt/Au NPs及Au NPs含有分散劑對JC之MTT試驗及T-test分析 234.3.3 Pt/Au NPs及Au NPs未含有分散劑對SKOV-3之MTT試驗及T-test分析 244.3.4 Pt/Au NPs及Au NPs未含有分散劑對JC之MTT試驗及T-tes

t分析 254.4光熱治療 264.4.1 Pt/Au NPs及Au NPs升溫取線 264.4.2 Pt/Au NPs及Au NPs對SKOV-3光熱治療試驗及T-test分析 274.4.3 Pt/Au NPs及Au NPs對JC光熱治療試驗及T-test分析 284.5動物實驗 294.5.1動物體重觀察 294.5.2動物光熱治療升溫取線 294.5.3動物腫瘤體積估算 304.5.4動物組織病理切片 31第五章 結論 33參考文獻 34附件 88